منابع مشابه
Role of Cl channels in Cl-dependent Na/H exchange.
A novel Na/H exchange activity that requires Cl was recently identified in the apical membrane of crypt cells of the rat distal colon. This study explores the nature of the coupling of Cl and Na/H exchange. A concentration of 100 μM 5-nitro-2-(3-phenylpropylamino)benzoic acid, a Cl channel blocker, inhibited the Cl dependence of both proton gradient-driven22Na uptake from crypt cell apical memb...
متن کاملCl- channels of the distal nephron.
Cl- currents were observed under whole cell clamp conditions in cells of the rat cortical collecting duct (CCD), connecting tubule (CNT), and thick ascending limb of Henle's loop (TALH). These currents were much larger in intercalated cells compared with principal cells of the CCD and were also larger in the TALH and in the CNT compared with the CCD. The conductance had no strong voltage depend...
متن کاملCa2+-activated Cl- channels at a glance.
Cl channels are membrane proteins that are responsible for the passive flow of Cl into and out of the cell. The Ca-activated Cl channels (CaCCs) are attracting a lot of attention lately. The molecular identity of these channels remained elusive (for a review, see Hartzell et al., 2005) until anoctamin 1 and anoctamin 2 (in mammals ANO1 and ANO2, respectively; in Xenopus TMEM16A and TMEM16B, res...
متن کاملAnion Permeation in Ca2+-Activated Cl− Channels
Ca(2+)-activated Cl channels (Cl(Ca)Cs) are an important class of anion channels that are opened by increases in cytosolic [Ca(2+)]. Here, we examine the mechanisms of anion permeation through Cl(Ca)Cs from Xenopus oocytes in excised inside-out and outside-out patches. Cl(Ca)Cs exhibited moderate selectivity for Cl over Na: P(Na)/P(Cl) = 0.1. The apparent affinity of Cl(Ca)Cs for Cl was low: K(...
متن کاملA Blind Hammerstein Diversity Combining Technique for Flat Fading Channels
Diversity combining techniques play an important role in combating the destructive effects of channel fading in wireless communication systems. In this work we present a blind diversity combining technique for Rayleigh flat fading channels based on Hammerstein type filters. We show that the performance of this technique is very close to ideal MRC system which is accepted as an optimum receiver ...
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ژورنال
عنوان ژورنال: Cellular and Molecular Life Sciences
سال: 2005
ISSN: 1420-682X,1420-9071
DOI: 10.1007/s00018-005-5336-4